Size of the Closed System Transfer Devices Market in 2023


Closed system transfer devices are used to transfer medication from one reservoir to another while minimizing the risk of drug aerosols, sharps exposure, drug contamination, and hazardous drug exposure. It prevents the entry of external contaminants into the system & the escape of hazardous drugs outside the system mechanically.


In 2021, the market value of closed system transfer devices was worth USD 785.24 billion, and by 2030 it will reach USD 3.8 billion, growing at a 19.2% CAGR during the forecast period.


In the upcoming years, the market will expand as a result of the rising global healthcare spending and the rapid advancements in medical science. Also, the expanding use of closed system transfer devices in numerous therapeutic areas and the rising deployment of automated drug-compounding robots will fuel market expansion throughout the projection period.


Market Dynamics




The rise in oncology product approvals and the rising incidence of cancer contribute to the market’s overall expansion. The GLOBOCAN 2020 report estimates that there will be approximately 19,292,789 new cases of cancer globally in 2020. By 2040, this number will increase to 28,887,940. The large population of cancer patients, driving demand for cutting-edge drug delivery methods, will contribute to the market’s expansion for closed system transfer devices.


The closed system drug transfer devices market is driven by expanding demand from nations like China, Japan, and India, as well as rising healthcare costs and drug approvals. Growing safety concerns, an increase in the production of biohazardous waste, and a growing demand for better healthcare services all contribute to the market’s expansion.




The high implementation costs associated with closed system transfer devices immediately raise the price of services and goods. Additionally, market growth may be hampered by faulty regulatory guidelines in developing and undeveloped nations.




Drugs known as cytotoxic agents are intended to kill rapidly and uncontrollably proliferating cells. The use of this medication is rising quickly in the healthcare industry worldwide, and it will expand in the coming years.


Monoclonal antibodies, the Guerin strain of Mycobacterium Bovis (BCG). And other non-cytotoxic medications like Bacillus of Calmette are also in great demand and will expand at a quick rate in the future.


Market Segmentation


By Device Type


On the basis of device type, the membrane-to-membrane system ruled the entire market with 63% of the revenue share. The membrane-to-membrane transference devices isolate the medical preparation using a dual membrane system between the syringe and vial. The largest share is due to the ease of operation and reduced risk of contamination attributed with Double Membrane Containment Systems.


By Component


On the basis of component, the vial access segment led the entire market with the largest revenue share. The largest market share is due to oncology doctors’ growing usage of CSTD products and vial access devices.

The medical care framework has seen tremendous difficulties because of the Coronavirus pandemic. All short term therapies were deferred or limited during the Coronavirus pandemic to decrease the gamble of viral transmission as most constant treatments were viewed as non-earnest. Notwithstanding, with the appearance of the Coronavirus contamination, enormous scope inoculations were played out everywhere, which significantly helped the shut framework move gadgets market. An article named “A Without needle Stream Infusion Framework for Controlled Delivery and Rehashed Biopharmaceutical Conveyance” distributed in the diary of Drugs in November 2021 concentrated on the fruitful plan and working model of an air-driven sans needle fly injector, which is a kind of needleless shut framework move gadget, for use during the huge scope Coronavirus immunizations.

The model had a medication conveyance productivity of 96.7% for 0.2 mL/shot infusions. And 97.8% medication move proficiency at 0.5 mL/shot. The proposed model could be utilized industrially, as the WHO rules for infusion gadgets require 86% or higher precision. Such advancements in shut framework move gadgets are probably going to add to the development of the market over the estimate period.


By En-User


On the basis of end-user, the hospital & clinic segment was the market leader with a significant revenue share. The largest share of this segment is due to the hospitals’ substantial financial resources and the pressing need for regulatory requirements.

There has been an ascent in the pervasiveness of constant sicknesses like diabetes, malignant growth, coronary illness, and stroke. Other way of life infections like constant lung sickness, persistent kidney illness. And Alzheimer’s illness have additionally been on the ascent throughout the last ten years. In 2021, the Middle for Infectious prevention and Counteraction has recorded that in the US, six of every ten grown-ups have no less than one ongoing sickness and four out of ten grown-ups have at least two. The rising pervasiveness of such constant illnesses has additionally expanded the advancements in the needleless medication conveyance framework.

The huge predominance of constant infections, for example, disease. And diabetes is suppose to push the development of the market over the gauge period. The IDF Diabetes Map book 10th version by the Global Diabetes League show that around 537 million grown-ups are impact by diabetes starting around 2021. The quantity of cases is project to ascend to 643 million by 2030 and to 783 million by 2045. The sort 1 diabetic patients expect insulin to be infuse for controlling the glucose levels. Organizations, for example, Insujet give without needle answer for insulin treatment, which are probably going to add to the development of the needleless frameworks portion over the conjecture period.



Regional Analysis 


North America was the biggest regional market in 2022. The largest share is due to the U.S. Food and Drug Administration. And other North American regulatory organizations’ efforts to assure patient safety. And the region’s growing number of oncology medicine approvals. Asia-Pacific will expand significantly due to reasons like the expansion of cancer research. And the rising incidence of the disease in the region’s developing and impoverished nations. Additionally, using closed system transfer devices to combat dangerous drugs in the area. And ongoing efforts by public and private organizations will promote regional growth.

The Needleless framework portion is expect to develop at remarkable rates inferable from the benefits. For example, without needle move of the medicine, new item dispatches, and wellbeing. The benefits like usability, and okay of tainting guarantee the wellbeing expected to build the use of the needleless exchange gadgets over the gauge period.


Recent development


Zephyrus Innovations, a privately held medical device company that designs and manufactures safety syringes. And Closed System Transfer Devices (CSTDs), has received its first FDA 510(k) approval for its Aeroject 3ml safety syringe.

The FDA has approved ublituximab-xiiy for treating adults with relapsing multiple sclerosis (RMS), including relapsing-remitting disease, clinically isolated syndrome, and active secondary progressive disease.

The rising pervasiveness of disease all over the planet and the ascent in the quantity of oncology item endorsements are central point ascribing to the development of the concentrated on market. As per the GLOBOCAN 2020 report, the all out number of individuals on the planet impacted by malignant growth in 2020 records for around 19,292,789 cases. The number is assess to ascend to 28,887,940 cases by 2040. The colossal number of individuals impact by disease, spurring an interest for inventive medication conveyance innovations is suppose to add to the development of the shut framework move gadgets market.


North America is suppose to have a huge piece of the pie in shut framework move gadgets market. The development is credit to drives taken by the U.S. Food and Medication Organization and other administrative bodies in North America to guarantee patient wellbeing combined with the rising number of oncology drug endorsements in the locale. The Asia Pacific locale is project to have an eminent development rate inferable from the variables. For example, the expansion in disease research, the developing commonness of malignant growth in creating and immature nations of the district.


Key Players 


  • JMS
  • Becton
  • Dickinson and Company
  • Braun Melsungen
  • Corvida Medical
  • CODAN Medizinische Geräte
  • ICU Medical
  • Equashield
  • Yukon Medical
  • Corvida Medical
  • Simplivia Healthcare
  • Caragen
  • Baxter International



In 2021, the market value of closed system transfer devices was worth USD 785.24 billion. And by 2030 it will reach USD 3.8 billion, growing at a 19.2% CAGR during the forecast period. Technological improvements and large investments in research & development drive market expansion. Global demand for closed system drug transfer devices has increased. Due to new product releases and acquisitions by top market players.

Restricting the openness to dangerous medications/synthetics is significant because of the potential mischief that could cause to medical care laborers and patients in medical services/clinical arrangements. Because of the expanded frequency of perilous medication openings in numerous nations. The administrative specialists have taken numerous drives to guarantee the wellbeing of patients and medical services laborers. Inferable from the variables, for example, developing mindfulness in regards to use of shut framework move gadgets. And expanded oncology drug endorsements worldwide shut framework move gadgets (CSTD) market is suppose to altogether develop. Moreover, the mechanical headways in shut framework move gadgets expected to help the market development.

Nonetheless, the significant expense engaged with the execution of shut framework move gadgets straightforwardly expands the expense of treatment/items. Moreover, ill-advised administrative rules in creating and immature nations might hamper market development over the gauge period.


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